Pain-Free Cryotherapy & E50 Exosome Treatment in Harley Street, London
Experience advanced needle-free skin rejuvenation and pain-free aesthetic treatments at our Harley Street clinic using the innovative Target Cool cryotherapy system and E50 Exosomes.
Designed for clients who want natural, regenerative results without discomfort, this treatment combines precision cooling with next-generation skin bio-stimulation.
What is exosome therapy?
Exosome therapy is a regenerative skin treatment that uses cell-derived messengers to support collagen production, skin repair and overall skin health.
What Is Target Cool Cryotherapy?
Target Cool is a medical-grade cryotherapy device that delivers controlled cooling to the skin to:
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Reduce pain during aesthetic procedures
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Enhance absorption of active ingredients
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Support faster skin recovery
By lowering the skin’s temperature, the treatment helps improve circulation and reduce inflammation, while also temporarily slowing pain signals in the treated area.
This makes it ideal for patients who:
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Dislike needles
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Have low pain tolerance
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Want a more comfortable aesthetic experience
What Are E50 Exosomes?
E50 Exosomes are nano-sized biological messengers naturally released by cells that support communication between skin cells and regeneration processes.
They contain:
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Proteins
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Lipids
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Growth factors
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Amino acids
As we age, natural exosome production declines—contributing to:
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Fine lines and wrinkles
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Loss of elasticity
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Slower skin repair
By reintroducing exosomes into the skin, treatments aim to stimulate collagen, improve texture, and support overall skin health.
How This Treatment Works
This treatment combines two advanced technologies:
1. Cryotherapy Cooling
The Target Cool device rapidly cools the skin to:
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Numb the treatment area
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Reduce discomfort
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Improve circulation
2. High-Speed Delivery of Exosomes
Exosomes are delivered as micro-particles that penetrate the upper skin layers, helping to:
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Trigger collagen production
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Support skin regeneration
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Enhance absorption of active ingredients
The result is a non-invasive, needle-free skin rejuvenation treatment with minimal downtime.
Key Benefits
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Pain-free or significantly reduced discomfort
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Needle-free delivery option available
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Improved skin hydration and glow
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Supports collagen and elastin production
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Reduced inflammation and redness
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Faster recovery after aesthetic treatments
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Suitable for sensitive or anxious patients
Who is this for?
This treatment is ideal for:
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Patients who want pain-free aesthetic procedures
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Individuals with sensitive skin
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Clients looking for non-invasive skin rejuvenation
What Can It Treat?
This treatment is commonly used for:
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Fine lines and wrinkles
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Dull or tired skin
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Skin laxity and loss of firmness
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Post-treatment recovery (e.g. after microneedling)
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Skin inflammation and redness
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Early signs of ageing
It can also be used alongside other aesthetic treatments to enhance results.
Additional Uses of Target Cool
The Target Cool system can also be used for:
Skin Tag Removal
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Quick, targeted freezing treatment
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Minimal discomfort
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No downtime
Sun Spots & Age Spots
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Precision cryotherapy removal
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Gradual healing over 1–2 weeks
What Results Can You Expect?
Following treatment, patients typically notice:
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Brighter, more radiant skin
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Improved texture and smoothness
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Increased firmness over time
For optimal results, a course of treatments may be recommended depending on your skin goals.
Why Choose Our Harley Street Clinic?
At Austin Brewer Facial Aesthetics, treatments are performed by the highly experienced, medically trained practitioner, Austin Brewer, specialising in advanced facial aesthetics.
We focus on:
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Natural, subtle results
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Patient safety and clinical excellence
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Bespoke treatment plans tailored to you
Located in Harley Street, London, our clinic is trusted by clients seeking premium, medically-led aesthetic treatments.
Frequently Asked Questions
Is the treatment really pain-free?
Most patients experience little to no discomfort due to the cooling effect, which acts similarly to local numbing.
Is there any downtime?
No—most patients return to normal activities immediately.
How long does the treatment take?
Typically 30–60 minutes depending on the area treated.
How many sessions do I need?
A course of treatments is often recommended for best results, depending on your skin condition.
Is this better than microneedling?
It can be used as an alternative or combined with microneedling for enhanced results.
Book a Consultation
If you’re looking for pain-free aesthetic treatments in Harley Street or want to explore exosome skin rejuvenation, book a consultation today.